MyBioSource.com's RABBIT ANTI HUMAN INTERLEUKIN-17 is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Functional Assay, Immunofluorescence, Immunohistochemistry, and Western Blot. The RABBIT ANTI HUMAN INTERLEUKIN-17 Antibody was generated using IL-17, IL17, IL17A, IL17F, Interleukin 17, and Interleukin 17A as the antigen and it reacts with Human.
Description
Rabbit anti Human Interleukin-17 antibody recognizes human IL-17 (Interleukin-17/17A), a 32kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction